Two men have died and a woman has been left fighting for life after a horror two-vehicle crash. 

The incident occurred at the intersection between Gin Gin Road and Line Road, in South Kolan, near Bundaberg, in south-east Queensland at 2.44pm on Saturday. 

A 78-year-old man from Bullyard and a 55-year-old man from Bundaberg Park Village were both killed in the smash. 

A silver Holden Commodore that was travelling on Gin Gin Road is understood to have collided with a grey Chrysler 300c at the intersection.

A 75-year-old woman, who was also travelling in the Chrysler, suffered life-threatening injuries and was rushed to Bundaberg Base Hospital. 

Rescuers from the Queensland Fire Department also attended the scene and a LifeFlight helicopter was also called in to assist emergency services. 

The road was closed for several hours. 

Queensland Police have urged anyone with information or dashcam footage to come forward. 

Two men have died after a horror two-vehicle crash at an intersection in in South Kolan, near Bundaberg, in Queensland, on Saturday afternoon (pictured street view)

Investigations into the incident are ongoing. 

Daily Mail Australia has contacted Queensland Health for comment.